IV Therapy Treatment for Depression via Ketamine, a.k.a. Special K, the hallucinogenic raver staple appreciated for its tranquilizing, dissociative high, has made a bit of a splash in the media recently, due in part to its promising potential as an antidepressant.
The World Health Organization lists ketamine among its tally of “essential medicines” thanks to the drug’s broad use as an analgesic (painkiller). This allows doctors to prescribe the substance “off-label” for mental disorders like clinical depression. The results are extremely promising.
Allegedly showing results in hours rather than weeks, ketamine affects the levels of the neurotransmitter glutamate, whereas traditional antidepressants like Prozac instead focus on serotonin receptors. Administering ketamine by IV has been shown to rapidly increase levels of these synaptic proteins, with significant effects observed after a mere two hours.